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http://hdl.handle.net/11690/3833
Autor(es): | De Cesaro, Maiara Cristina Souza, Andressa de Stahnke, Douglas Nunes Medeiros, Liciane Fernandes Silva, Fernanda Rabaioli da |
Título: | Prophylaxis Against Covid-19: Analysis Of The Supply of Hydroxychloroquine, Ivermectin And Azithromycin and Covid-19 Cases and Deaths |
Palavras-chave: | Hidroxicloroquina;Ivermectina;Azitromicina;Pandemia do COVID-19;Mortalidade;Número de casos |
Data do documento: | 2023 |
Editor: | Saúde e Desenvolvimento Humano |
Citação: | CESARO, M. C. et al. Prophylaxis Against Covid-19: Analysis Of The Supply of Hydroxychloroquine and Ivermectin and Covid-19 Cases and Deaths. SAÚDE E DESENVOLVIMENTO HUMANO, v. 11, p. 1-11, 2023. Disponível em: https://revistas.unilasalle.edu.br/index.php/saude_desenvolvimento/article/view/10214 Acesso em: 22 fev. 2024. |
Resumo: | Introduction: The evidence suggesting the possible use of Hydroxychloroquine, Ivermectin and Azithromycin in the management of COVID-19 is still inconclusive. Objective: This is an interrupted time series ecological study where a temporal analysis of the consumption of hydroxychloroquine, ivermectin and azithromycin in the pre-pandemic and pandemic periods in the São Lourenço do Oeste/ Santa Catarina, was performed, a Brazilian city. Material and Methods: Data were collected monthly from January 2018 to March 2021 directly from pharmacies/drug stores for medications, and from April 2020 to March 2021 for COVID-19. The temporal analysis was performed using the Prain-Winsten test. Associations between variables (drugs and COVID-19 data) were made by Spearman’s correlation test. Results: The supply of ivermectin (coeffi cient, 7.71 p=0.005) and hydroxychloroquine increased (coeffi cient 26.84, p=0.021) in the pandemic; and azithromycin remained stable (p≥ 0.05). There was a positive correlation between new cases of COVID-19 and the supply of azithromycin, hydroxychloroquine and ivermectin (Spearman rho 0.857, 0.760 and 0.741 p<0.01, respectively) and a positive correlation between deaths with azithromycin (Spearman rho 0.690, p<0.01) and hydroxychloroquine (Spearman rho 0.617, p<0.05). Conclusions: According to our data, it is possible to infer that the increased supply of ivermectin, azithromycin or hydroxychloroquine was not able to reduce new cases or deaths by COVID-19, showing no eff ectiveness as prophylaxis of this disease. |
Aparece nas coleções: | Artigo de Periódico (PPGSDH) |
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10214-n3-Ok.pdf | Open Access | 351,38 kB | Adobe PDF | Visualizar/Abrir |
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