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http://hdl.handle.net/11690/3384
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Campo DC | Valor | Idioma |
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dc.contributor.author | Medeiros, Helouise R. | - |
dc.contributor.author | Assumpcao, José A. F. | - |
dc.contributor.author | Medeiros, Liciane Fernandes | - |
dc.contributor.author | Stapenhorst, Martina | - |
dc.contributor.author | Nunes, Lara | - |
dc.contributor.author | Henckes, Nicole A. C. | - |
dc.contributor.author | Cruz, Carolina Uribe | - |
dc.contributor.author | Oliveira, Fernanda S. O. | - |
dc.contributor.author | Caumo, Wolnei | - |
dc.contributor.author | Cirne-Lima, Elizabeth O. | - |
dc.contributor.author | Torres, Iraci L. S. | - |
dc.date.accessioned | 2023-02-15T16:36:27Z | - |
dc.date.available | 2023-02-15T16:36:27Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | MEDEIROS, H. R. et al. Static magnetic stimulation induces cell-type specific alterations in the viability of SH-SY5Y Neuroblastoma cell line. Anticancer Research, v.40, n. 9, p. 5151-5158, 2020. Disponível em: https://ar.iiarjournals.org/content/40/9/5151.long. Acesso em: 15 fev. 2023. | pt_BR |
dc.identifier.uri | http://hdl.handle.net/11690/3384 | - |
dc.description.abstract | Background/Aim: Magnetic stimulation is used in the treatment of a diversity of diseases, but a complete understanding of the underlying mechanisms of action requires further investigation. We examined the effect of static magnetic stimulation (SMS) in different cell lines. Materials and Methods: A culture plate holder with attached NeFeB magnets was developed. Different magnetic field intensities and periods were tested in tumoral and non-tumoral cell lines. To verify the cellular responses to SMS, cell viability, cell death, cell cycle and BDNF expression were evaluated. Results: Exposure of SH-SY5Y cells to SMS for 24 hours led to a decrease in cell viability. Analysis 24 h after stimulation revealed a decrease in apoptotic and double-positive cells, associated with an increase in the number of necrotic cells. Conclusion: The effects of SMS on cell viability are cell type-specific, inducing a decrease in cell viability in SH-SY5Y cells. This suggests that SMS may be a potential tool in the treatment of neuronal tumors. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | Anticancer Research | pt_BR |
dc.rights | Open Access | en |
dc.subject | Static magnetic stimulation | pt_BR |
dc.subject | Cell cycle | pt_BR |
dc.subject | Cell death | pt_BR |
dc.subject | Cell viability | pt_BR |
dc.subject | Neuroblastoma | pt_BR |
dc.title | Static magnetic stimulation induces cell-type specific alterations in the viability of SH-SY5Y Neuroblastoma cell line | pt_BR |
dc.type | Artigo | pt_BR |
Aparece nas coleções: | Artigo de Periódico (PPGSDH) |
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medeirosetal.pdf | Open Access | 836,71 kB | Adobe PDF | Visualizar/Abrir |
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